Step 1: Understanding the condition of trisomy 21. Trisomy of chromosome 21 leads to Down syndrome, a genetic disorder caused by an extra copy of chromosome 21.
Step 2: Symptoms of Down syndrome. Key features include: - Furrowed tongue (i) - Characteristic palm crease (ii) Other traits, such as developmental delays, may also occur.
List-I | List-II |
(A) Thalassemia | (I) 47, XXY |
(B) Klinefelter’s syndrome | (II) Sex-linked recessive disorder |
(C) Turner’s syndrome | (III) 45, XO |
(D) Colour blindness | (IV) Autosomal recessive disease |