Question:

A man is having difficulty sleeping during the night. He has the habit of drinking coffee before bedtime. What is the role of caffeine in wakefulness?

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Caffeine blocks adenosine receptors, preventing the sleep-promoting effects of adenosine and thereby promoting wakefulness.
Updated On: Mar 24, 2025
  • Blocks adenosine action and causes wakefulness
  • Activates locus coeruleus and causes wakefulness
  • No role in maintaining wakefulness if taken 1hr before sleep
  • Activates histamine release and prevents sleep
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The Correct Option is A

Solution and Explanation

Caffeine works as a stimulant by blocking adenosine receptors in the brain. Adenosine is a neurotransmitter that promotes sleep, and by blocking its action, caffeine helps to promote wakefulness and reduce the sensation of fatigue.
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