The scenario you described could be caused by both bacteria and fungi, and involves deeper tissue involvement beyond just the skin. Sinuses with discharging granules on the leg can be indicative of a deeper infection that has spread from the skin to underlying tissues, such as the subcutaneous tissue or bone. This type of infection can result from a variety of causes, including both bacteria and fungi, and can be difficult to treat if left untreated for an extended period of time. Lymphocyte accumulation may be present in the affected area as part of the body’s immune response to the infection.
The spread of the infection to deeper tissues can occur through a variety of routes, including the hematogenous route, where the infection spreads through the bloodstream to distant sites. It is important to obtain a proper diagnosis and prompt treatment for this type of infection to prevent further spread and complications. This involves examining a sample of the discharging material for laboratory analysis, such as culture and microscopic examination, to determine the specific cause of the infection and guide appropriate treatment.