Question:

A 58-year-old male chronic smoker diabetic and having normal coronaries presents with bilateral calf claudication. Femoral pulses are palpable but distal pulses are absent with bilateral ABI of 0.5 and no rest pain or tissue loss. He has following doubts after reading about peripheral vascular disease on internet and needs a counselling session with the treating vascular surgeon.
What are the components of best medical management you would advise to him?

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For patients with PAD, managing underlying risk factors (like diabetes, smoking, and hypertension) and using antiplatelet therapy are essential for effective management.
Updated On: Dec 12, 2025
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Solution and Explanation


Step 1: Understanding the treatment goals.
The main goal of medical management in peripheral arterial disease is to alleviate symptoms, prevent disease progression, and reduce the risk of complications, including limb loss and cardiovascular events. Treatment should address the patient's risk factors and include lifestyle modifications.

Step 2: Components of best medical management.
- Smoking cessation: Smoking is a major risk factor for PAD and exacerbates disease progression. The patient should be encouraged to stop smoking.
- Glycemic control: As the patient is diabetic, controlling blood sugar levels is crucial in preventing further vascular damage.
- Antiplatelet therapy: Medications like aspirin or clopidogrel should be prescribed to reduce the risk of thrombotic events.
- Statins: Statins should be prescribed to control cholesterol levels and reduce the risk of cardiovascular events.
- Exercise therapy: Supervised walking programs can improve symptoms of claudication and increase walking distance.
- Blood pressure control: Hypertension should be managed effectively to reduce the strain on blood vessels.

Step 3: Conclusion.
The best medical management for this patient includes smoking cessation, blood sugar control, antiplatelet therapy, statin therapy, regular exercise, and blood pressure management. These measures can significantly reduce the progression of PAD and improve quality of life.
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