Question:

A 40-year-old female with a lump in the breast measuring 5 X 6 cm. The HPE (Histopathological Examination) given in the image, what is the likely diagnosis? 

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Phyllodes tumors are distinctive for their leaf-like histological appearance and are treated by surgical excision. They can recur, and malignant variants require more aggressive treatment.
Updated On: Jul 9, 2025
  • Phyllodes tumour
  • Fibroadenoma
  • Breast carcinoma
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The Correct Option is A

Solution and Explanation

The patient is a 40-year-old female presenting a breast lump measuring 5 x 6 cm. Given this information and the histopathological examination (HPE) details provided in the image, we need to determine the likely diagnosis from the options provided.

The options are:

  • Phyllodes tumour
  • Fibroadenoma
  • Breast carcinoma

To solve this problem, we need to closely consider the characteristics of the lump and correlate it with the possible diagnoses:

  • Phyllodes tumour: These are rare fibroepithelial tumors that can grow quickly and are generally larger upon presentation. Most common in women aged 40-50.
  • Fibroadenoma: Common benign tumors in young women, usually smaller and well-circumscribed.
  • Breast carcinoma: Malignant tumors of varying size, often presenting with additional symptoms like skin changes or lymph node involvement.

Examining the size of the lump (5 x 6 cm) and the patient's age (40 years), a Phyllodes tumour is more consistent with this presentation. Fibroadenomas are typically smaller and more common in younger individuals, while breast carcinoma would likely present additional symptoms or smaller sizes in initial detection stages.

Therefore, the most likely diagnosis is Phyllodes tumour.

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