List of top Pharmaceutical Chemistry Questions

Hot stage microscopy is an important tool in preformulation studies for the study of
Match the following adrenergic drugs with their receptor affinity
(1) Epinephrine
(2) Noradreanline
(3) Phenylephrine
(4) Dobutamine		(a) More alpha 1, no beta 1, beta 2 & dopamine 
(b) More alpha 1 & beta 1, less beta 2, no dopamine 
(c) More beta 1 & Beta 2, no alpha 1 and dopamine 
(d) More alpha 1 & beta 1, no beta 2 & dopamine
All the dopaminergic agonists having affinity for D2 receptors are clinically used in following conditions except
Reduction of imines to give amines in protic solvents can be carried out by one of the following reagents. Select the correct reagent
Which among the following describe the characteristic features of Tetracyline
At pH 5, the ratio of the protonated to unprotanated forms of morphine pKa 7 would be
Which of the following is NOT suitable as a post-coital contraceptive
2', 3'-Didehydro-3'-deoxy thymidine is the chemical name of which of following antiviral agents
An antibiotic thatn resembles the 3' end of a charged tRNA molecule is
When morphine is heated at 140°C under pressure, with strong HCL, it converts pnto:
Match the antimalarial drugs with their modes of action
(1)Artemisinin(P)Inhibition of parasite mitochondrial electron Transport
(2)Pyremethamine(Q)Inhibition of heme polymerase
(3)Quinine(R)Generation of oxygen and carbon centered redicals
(4)Atovaquone/Proguanil(S)Inhibition of dihydrofolate reductase
Oseltamivir is antiviral drug. It produces its action by inhibiting which enzymes
Which of the following agents act as hypoglycemic as ATP sensitive potassium channel blocker
In the following drug find out the Potassium Sparing Diuretics
What is the 6-methyl derivative of erythromycin
In the diagnosis of myasthenia gravis, only one of the following drugs will be used as a drug of choice
A series of α-acylureido penicillin's like azlocillin, mezloacillin, and piperacillin are superior because of
Out of the following anti cancer drug cardio toxicity is seen in
The drug of choice in prolonged febrile convulsions is:
The hydroxyl derivative of cymene is called as what
(P) Thymol
(Q) Carvacrol
(R) Menthol
(S) Cumene
The choice of route of administration plays an important role in action of directly acting cholinomimetic. Adverse effect of choline esters that may be avoided by selection of an appropriate route of administration is
Tranexamic acid is
Zink chloride is added to mouth wash because it acts as
What is the renal clearance of a substance, if its concentration in plasma is 10mg, concentration in urine is 100 mg and urine flow is 2 ml/min
All of the following ACE inhibitors are prodrugs EXCEPT