List of top Biology Questions asked in GATE Biotechnology

Match the immune tolerance mechanisms in Group I with their respective outcomes in Group II

Group IGroup II
P) Anergy1) Elimination of activated T-cells after antigen clearance
Q) Activation-induced cell death2) Inhibition of auto-reactive T-cells at periphery
R) Receptor editing3) Unresponsiveness to antigens due to lack of co-stimulatory molecules
S) Regulatory T-cells4) Elimination of auto-reactive B-cells
Match the types of RNA in Group I with their corresponding function in Group II.
Group I:
P. mRNA
Q. rRNA
R. miRNA
S. tRNA
Group II:
1. Serves as adaptors between mRNA and amino acids during protein synthesis
2. Regulates post-transcriptional gene expression
3. Codes for proteins
4. Forms the core of the ribosome structure and catalyzes protein synthesis
Which one of the following is required for the development of B-cells in the bone marrow?
Which one of the following statements is TRUE about leghemoglobin?
Which one of the following drugs is NOT an immune checkpoint inhibitor?
Dendritic cells are involved in cross-presentation of antigens. Which of the following protein(s) is(are) required for cross-presentation?
P. Basic leucine zipper ATF-like transcription factor 3 (BATF3)
Q. Membrane associated ring-CH-type finger 1 (MARCH-1)
R. Solute carrier family 10 member 1 (SLC10A1)
S. Class II-associated invariant chain peptide (CLIP)
Determine the correctness or otherwise of the following Assertion [a] and the Reason [r].
Assertion [a]: In multicellular organisms, cells of different lineages have different gene expression profiles.
Reason [r]: Alternative splicing is the only mechanism to generate protein diversity.
Determine the correctness or otherwise of the following Assertion [a] and the Reason [r].
Assertion [a]: Chromosome mutations can change the structure of chromosomes.
Reason [r]: All chromosome mutations arise due to nondisjunction of chromosomes during mitosis or meiosis.
C-value paradox refers to
Acetylcholine released by the parasympathetic nerves has which one of the following functions in the heart pacemaker cells?
Eukaryotic transcription is carried out by