Question:

Which one of the following never occurs during mitotic cell division?

Updated On: May 2, 2025
  • Spindle fibres attach to kinetochores of chromosomes
  • Movement of centrioles towards opposite poles
  • Pairing of homologous chromosomes
  • Coiling and condensation of the chromatids
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The Correct Option is C

Solution and Explanation

During mitotic cell division, several critical processes occur to ensure accurate cellular replication. Let's examine each of the given options:
  • Spindle fibres attach to kinetochores of chromosomes: This process is crucial in mitosis for the separation of sister chromatids. Spindle fibres connect to kinetochores on the chromosomes, which allows for the equal distribution of chromatids into the daughter cells.
  • Movement of centrioles towards opposite poles: In mitosis, centrioles play a role in organizing microtubules into spindle fibres. They migrate to opposite poles of the cell to establish the poles of the mitotic spindle, essential for chromatid separation.
  • Pairing of homologous chromosomes: This occurs during meiosis, not mitosis. In meiosis, homologous chromosomes pair during prophase I, allowing for genetic recombination. In mitosis, homologous chromosomes do not pair; instead, sister chromatids are separated.
  • Coiling and condensation of the chromatids: This occurs in prophase of mitosis where chromatin fibres condense to become visible chromosomes, facilitating their separation.
Given these descriptions, the correct answer is that pairing of homologous chromosomes never occurs during mitotic cell division. This is specific to meiotic cell division.
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Concepts Used:

Cell Cycle and Cell Division

Cell Cycle:

The sequence of events by which a cell copies itself synthesizes other constituents of the cell and eventually splits into two daughter cells is termed the cell cycle. The cell synthesizes all its constituents in a sequential pattern to make sure the proper division and distribution of components that occurs between the two daughter cells. Therefore, we can say that the cell cycle is the period of time between the development of new daughter cells and their further division.

Stages of Cell Cycle:

The cell cycle can be sub-divided into an additional category of Interphase. Meanwhile, the Interphase can be branched into 3 further stages, such as:

  1. G1 Phase - “Gap 1 Phase”
  2. S Phase - "Synthesis Phase"
  3. G2 Phase - "Gap 2 Phase"

Read More: Cell Cycle and Cell Division

Cell Division:

The division of the parent cells into two or more cells is called daughter cell, cell division takes place. In general, it occurs as a part of a larger cell cycle. All the cell reproduces by dividing into two, wherein each parental cell produces two daughter cells.

Stages of Cell Division:

Cell division can be widely divided into several sub-segments that result from Mitosis and Meiosis.

  1. Mitosis or (M Phase)
  2. Meiosis