Question

Which one of the following is true for piRNAs?

• A. piRNAs silence transposable elements in germ cells
• B. piRNA is the abbreviation of P-element interacting RNA
• C. piRNAs modify the 2′-OH of ribose with a methyl group
• D. piRNA is a long non-coding RNA

Hint:

PiRNAs are crucial for protecting the genome from transposable elements in germline cells, maintaining the integrity of the genome.

Answer 1

The Correct Option is A

piRNAs (Piwi-interacting RNAs) are a class of small RNAs that are primarily involved in silencing transposable elements in the germline.

Silencing Transposable Elements
piRNAs play a critical role in the regulation of transposons, particularly in germ cells, by binding to Piwi proteins. This interaction helps silence transposons and ensures genomic stability.

Thus, the correct answer is \( \boxed{A} \).