To determine which option cannot be folded into a package with a cross-section of an equilateral triangle, we need to visualize the folding process for each given layout. An equilateral triangle implies that all sides and angles are equal.
Analyzing the options:
1.

- This option can fold into an equilateral triangle. The trapezoidal and rectangular sections will align well to form a triangular prism with the required orientation.
2.

- This configuration supports the formation of an equilateral triangle with the rectangular tabs acting as the base and lateral supports.
3.

- This layout correctly folds into an equilateral triangle by wrapping segments symmetrically at appropriate fold lines.
4.

- By inspection, this layout does not align properly to form an equilateral triangle due to mismatched lengths and improper angle alignment. Unlike other options, folding these elements will not result in the required symmetry and equal angles for an equilateral triangle.
Conclusion: The layout shown in Option 4 cannot be folded into a package with an equilateral triangular cross-section.