Question:

Which of the following theories of Aging Process describe “Old age sets in, when the body cells exhaust the capacity of undergoing multiplication”?

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Hayflick = Human cell division limit = aging by senescence.
Updated On: July 22, 2025
  • Somatic Mutation Theory
  • Autoimmune Theory
  • Hayflick’s Theory
  • None of these
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The Correct Option is C

Solution and Explanation

The Hayflick’s Theory (also known as the Hayflick Limit) states that normal human cells have a limited capacity to divide and multiply.
Leonard Hayflick discovered that somatic cells divide only a certain number of times (about 50 times for human fibroblasts) before they stop multiplying — a phenomenon known as cellular senescence.
This exhaustion of cell division capacity contributes to aging as tissues lose the ability to renew and repair themselves.
Somatic Mutation Theory relates to genetic mutations accumulating with age, and the Autoimmune Theory relates to the immune system attacking its own cells — but neither directly describes the limit on cell multiplication.
Therefore, Hayflick’s Theory correctly describes this concept.
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