Question:

Which of the following statement is true for Barr body?

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Consider the role of X chromosome inactivation in females and its cytological appearance.
Updated On: Jan 4, 2025
  • It is a highly condensed chromosome.
  • It is an active X chromosome.
  • It is equivalent to the single Y chromosome of the male.
  • It is equivalent to the two X chromosomes of the female.
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The Correct Option is A

Solution and Explanation

The Barr body is the inactivated X chromosome in females, visible as a dense structure within the nucleus. This condensation ensures dosage compensation between males (with one active X chromosome) and females (with two X chromosomes). The inactive X chromosome is highly condensed and transcriptionally silent, contrasting with the active X chromosome.

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