- The gold number measures the protective power of a colloid, with higher values indicating better stability of colloidal dispersions.
- Tragacanth has the highest gold number among common protective colloids, making it highly effective in stabilizing colloidal solutions.
The gold number is a measure of the protective power of a colloid, defined as the minimum amount (in mg) of colloid required to prevent the precipitation of 10 mL of gold sol when added to the sol. A higher gold number indicates a greater protective power, meaning the colloid is better at stabilizing the sol. Among the options:
- Tragacanth has the highest gold number, indicating it has the greatest ability to protect a colloidal gold sol from precipitation. It is widely used in various pharmaceutical formulations for this reason.
- Acacia, Albumin, and Gelatin are also used as protective colloids, but their gold numbers are generally lower compared to Tragacanth. Thus, the correct answer is Tragacanth, which has a high gold number.
Why Other Options Are Incorrect:
- (A) Acacia: While Acacia is commonly used as a protective colloid, its gold number is not as high as Tragacanth.
- (C) Albumin: Albumin is a protein with protective colloidal properties, but it has a lower gold number compared to Tragacanth.
- (D) Gelatin: Gelatin has protective colloidal properties but does not have as high a gold number as Tragacanth.
List I Formulation Ingredient | List II Activity / Property | ||
Salts of d-glu- curonic acid poly-peptides and amino acids | Are pseudoplastic and plastic in nature | ||
Surfactants, both ionic and non-ionic | Form a multimolecular film around the dispersed droplets of oil in an o/w emulsion | ||
Magnesium aluminium silicate | Emulsifier belonging to the class of solid particles forms w/o emulsions | ||
Structured vehicles | Emulsifier belonging to the class of solid particles and forms o/w emulsion | ||
Have been used to bring about flocculation of suspended particles |