Acetylation is a Phase-II metabolism reaction, also known as conjugation. In this reaction, an acetyl group is added to the drug or its metabolite, increasing its water solubility and facilitating excretion. Phase-I reactions (like oxidation, reduction, and hydrolysis) modify the drug molecule, while Phase-II reactions involve conjugation with endogenous molecules like acetyl groups, sulfate, or glucuronic acid.
List I | List II |
---|---|
A. Vatsanabha | III. Aconitine |
B. Pita Karvira | I. Thevetin |
C. Gunja | IV. Abrin |
D. Ahiphena | II. Morphine |
List I | List II |
---|---|
A. Chitraka | II. Chitraka |
B. Bhallataka | III. Chakramarda |
C. Somaraji | I. Apamargakshara |
D. Bakul Puspa | IV. Kalhara |
List I | List II |
---|---|
A. Indian Jalap | II. Convolvulaceae |
B. Tooth Brush Tree | I. Apocynaceae |
C. Indian Oleander | I. Apocynaceae |
D. Ceylon Oak | III. Sapindaceae |
Match the following Class and their Drug:
(1) Alkylating (P) 5-fluorouracil
(2) Platinum analog (Q) Cisplatin
(3) Antimetabolite (R) Cetuximab
(4) EGF receptor inhibitor (S) Chlorambucil