Question

Which of the following is a loop diuretic?

• A. Spironolactone
• B. Furosemide
• C. Hydrochlorothiazide
• D. Acetazolamide

Hint:

Loop diuretics = “Furo for Fluid” — strong action, quick relief in fluid overload.

Answer 1

The Correct Option is B

Loop diuretics act on the thick ascending limb of the loop of Henle, inhibiting the Na\(^+\)-K\(^+\)-2Cl\(^-\) co-transporter, leading to increased excretion of sodium, potassium, and chloride, along with water. Furosemide is a potent loop diuretic, used in conditions like pulmonary edema, heart failure, and hypertension.
- Spironolactone is a potassium-sparing diuretic (aldosterone antagonist).
- Hydrochlorothiazide is a thiazide diuretic acting on the distal tubule.
- Acetazolamide is a carbonic anhydrase inhibitor.