Step 1: Understanding Clark’s formula. Clark’s formula calculates the child’s dose of a medication based on the child’s body weight, ensuring accurate dosing to avoid toxicity or underdosing. The formula is: \[ \text{Child’s Dose} = \frac{\text{Weight of the child (kg)}}{70} \times \text{Adult Dose} \] or, in pounds: \[ \text{Child’s Dose} = \frac{\text{Weight of the child (lb)}}{150} \times \text{Adult Dose}. \]
Step 2: Explanation of other formulas.
- (B) Fried’s formula: Based on the child’s age in months.
- (C) Young’s formula: Based on the child’s age in years.
- (D) Dilling’s formula: Also based on the child’s age in years, specifically for older children.
Conclusion. Since Clark’s formula considers the child’s body weight for dose calculation, option (A) is correct.
Match the following Class and their Drug:
(1) Alkylating (P) 5-fluorouracil
(2) Platinum analog (Q) Cisplatin
(3) Antimetabolite (R) Cetuximab
(4) EGF receptor inhibitor (S) Chlorambucil