Question

Which is the precursor for prostaglandins in humans?

• A. Eicosanoids
• B. Cyclooxygenase
• C. Linoleic acid
• D. Arachidonic acid

Hint:

Arachidonic acid is stored in the cell membrane and is the key starting material for the biosynthesis of inflammatory mediators like prostaglandins.

Answer 1

The Correct Option is D

Arachidonic acid is a polyunsaturated fatty acid that serves as the direct precursor for prostaglandins, thromboxanes, and leukotrienes—collectively called eicosanoids. Upon cellular stimulation, arachidonic acid is released from membrane phospholipids and is converted into prostaglandins through the cyclooxygenase (COX) enzyme pathway. These prostaglandins play crucial roles in inflammation, pain, fever, and other physiological functions.