Question

What is the meaning of charging of t-RNA?

• A. Linking of amino acid with cognate t-RNA
• B. Attachment of t-RNA with ribosome
• C. Translation of RNA
• D. Modification of RNA

Hint:

Charging of t-RNA is the first step in translation where t-RNA is loaded with its specific amino acid.

Answer 1

The Correct Option is A

Step 1: Concept of charging of t-RNA.
Charging of t-RNA refers to the process where an amino acid is chemically linked to its corresponding t-RNA by an enzyme called aminoacyl-tRNA synthetase. This prepares the t-RNA for protein synthesis.
Step 2: Analysis of options.
(1) Correct — This is the definition of charging of t-RNA.
(2) Incorrect, this occurs during translation, not charging.
(3) Incorrect, translation is the entire process of protein synthesis.
(4) Incorrect, charging is not modification but amino acid attachment.
Step 3: Conclusion.
Therefore, the correct answer is (1) Linking of amino acid with cognate t-RNA.