Question

What are x and y in the following set of reactions?

• A.

  

• B.

  

• C.

  

• D.

  

Hint:

Hofmann rearrangement: \begin{itemize} \item Converts amides → amines with loss of one carbon \item Goes through isocyanate intermediate \item Uses NaOBr/NaOH (bromine + base) \end{itemize}

Answer 1

The Correct Option is D

Step 1: Reaction (i) - Acid chloride formation
\[\text{COOH} \xrightarrow{\text{C}_6\text{H}_5\text{SO}_2\text{Cl/py}} \text{COCl}\] (x = COCl) Step 2: Reactions (ii) and (iii) - Hofmann rearrangement
\[\text{COCl} \xrightarrow{\text{NaOBr}} \text{Isocyanate} \xrightarrow{\text{H}_3\text{O}^+} \text{NH}_2\] (y = NH$_2$)