Step 1: Understanding the composition of Vitamin B12.
Vitamin B12 is a complex molecule that contains the metal cobalt at its core, coordinated to a corrin ring. This metal is essential for the biological activity of Vitamin B12.
Step 2: Analysis of options.
(A) Cobalt: Correct — Cobalt is the metal at the center of the Vitamin B12 structure.
(B) Magnesium: Magnesium is present in other biological compounds, but not in Vitamin B12.
(C) Iron: Iron is a component of hemoglobin and other heme proteins but is not found in Vitamin B12.
(D) Nickel: Nickel is found in some enzymes but not in Vitamin B12.
Step 3: Conclusion.
The correct answer is (A) because Vitamin B12 contains cobalt at its center.