Step 1: Understanding therapeutic equivalence. Therapeutic equivalence refers to two drugs that produce the same clinical effect and have a similar safety profile when administered in the same dosage form, strength, and route of administration. These drugs may differ in inactive ingredients but must demonstrate bioequivalence (similar rate and extent of absorption).
Step 2: Explanation of incorrect options.
- (A) Minimum Toxic Concentration (MTC): Refers to the lowest drug concentration at which toxic effects occur, unrelated to equivalence.
- (B) Minimum Effective Concentration (MEC): Refers to the lowest concentration required to produce a therapeutic effect, unrelated to equivalence.
- (D) Therapeutic window: Refers to the range between MEC and MTC, indicating drug safety, not equivalence.