We are asked to compute the sum of the series:
\[
\sum_{k=0}^{48} \frac{1}{(k + 1)(k + 2)}
\]
This can be rewritten as:
\[
\frac{1}{(k+1)(k+2)} = \frac{1}{k+1} - \frac{1}{k+2}
\]
Thus, the series becomes a telescoping series:
\[
\left( \frac{1}{1} - \frac{1}{2} \right) + \left( \frac{1}{2} - \frac{1}{3} \right) + \dots + \left( \frac{1}{49} - \frac{1}{50} \right)
\]
All intermediate terms cancel out, and we are left with:
\[
1 - \frac{1}{50}
\]
Thus, the sum is:
\[
1 - \frac{1}{50} = \frac{50}{50} - \frac{1}{50} = \frac{49}{50}
\]
Thus, the correct answer is (C).