Question

The cellular process which utilizes RNA-induced silencing complex to block gene expression is

• A. RNA editing
• B. RNA interference
• C. RNA polyadenylation
• D. RNA splicing

Hint:

RISC + siRNA/miRNA = RNA interference (post-transcriptional gene silencing).

Answer 1

The Correct Option is B

RNA interference (RNAi) is a post-transcriptional gene-silencing mechanism used by cells to regulate gene expression.
It involves small interfering RNAs (siRNAs) or microRNAs (miRNAs) that guide the RNA-induced silencing complex (RISC).
RISC binds to complementary mRNA sequences and either degrades the mRNA or blocks its translation.
RNA editing modifies RNA bases, not by using RISC.
Polyadenylation adds a poly-A tail to mRNA.
RNA splicing removes introns.
Thus, only RNA interference uses RISC to silence gene expression.