Question

The allergic immune response is characterized by the increased levels of:

• A. IgE
• B. IgA
• C. IgG
• D. IgM

Hint:

In allergic reactions, IgE antibodies bind to allergens and trigger the release of histamine, leading to the symptoms commonly associated with allergies, such as itching, sneezing, and swelling.

Answer 1

The Correct Option is A

Step 1: Understand allergic immune response.
An allergic immune response occurs when the immune system misidentifies a harmless substance (allergen) as a threat and mounts a defense against it. This leads to inflammation, itching, and other symptoms associated with allergies.

Step 2: Evaluate the antibodies involved in allergies.

• IgE: ✅ Correct. IgE is the key antibody in allergies. It binds to allergens and triggers mast cells and basophils to release histamine and other inflammatory chemicals.
• IgA: ❌ Involved in mucosal immunity (e.g., gut, saliva, tears), not typically linked with allergic reactions.
• IgG: ❌ Important for long-term immunity and pathogen neutralization but not primarily responsible for allergic symptoms.
• IgM: ❌ First antibody produced in primary immune response, not directly involved in allergic responses.

Step 3: Conclusion.
The antibody that plays the most important role in allergic immune responses is IgE.

Correct Answer: Option (1)