Question

RNA is a labile molecule due to the presence of:

• A. 3’-OH group
• B. 5’-OH group
• C. 4’-OH group
• D. 2’-OH group

Answer 1

The Correct Option is D

RNA is unstable due to the 2’-OH group, which makes it more prone to hydrolysis in cellular environments. The 2’-OH in RNA, compared to DNA’s absence of this hydroxyl group, contributes to its higher reactivity and lability, leading to faster degradation.