Question:

Reduction in pH of blood will -

Updated On: Apr 20, 2025
  • reduce the blood supply to the brain
  • decrease the affinity of hemoglobin with oxygen
  • release bicarbonate ions by the liver
  • reduce the rate of heart beat
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The Correct Option is B

Solution and Explanation

The correct answer is:

Option 2: decrease the affinity of hemoglobin with oxygen

Explanation:

The pH of blood plays a crucial role in the ability of hemoglobin to bind to oxygen. This is governed by the Bohr effect, which describes how changes in blood pH affect oxygen binding to hemoglobin.

Bohr Effect: When the pH of blood decreases (i.e., becomes more acidic), it causes a decrease in the affinity of hemoglobin for oxygen. This means that hemoglobin will release oxygen more readily to tissues that are actively metabolizing and producing more CO2 (which lowers the pH).

Why the Other Options Are Incorrect:

Option 1: While a decrease in pH can affect oxygen delivery, it does not directly reduce the blood supply to the brain. The body adjusts by increasing respiratory rate to remove CO2, which helps regulate blood pH.

Option 3: The release of bicarbonate ions by the liver is not directly related to blood pH reduction in this context. Bicarbonate ions act as a buffer in the blood to maintain pH, but the liver is not the primary regulator for the release of bicarbonate in response to pH.

Option 4: A decrease in pH does not directly reduce the rate of the heartbeat. However, extreme changes in blood pH (such as during severe acidosis) can affect the cardiovascular system.

Thus, decreased pH causes hemoglobin to release oxygen more readily to tissues, which is a key physiological response under certain conditions, like exercise or tissue inflammation.

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Concepts Used:

Blood

Blood is a fluid-like structure that is responsible for transporting oxygen and other nutrients to all the cells of the body. Blood shows characteristics of both tissues and fluid.

Composition of Blood:

Blood is composed of the below-mentioned parts:

  • Plasma
  • Blood Cells
  • Platelets

Types of Blood Cells:

The two types of blood cells present in the body are:

RBC (Red Blood Cells)

RBC’s are also known as Erythrocytes. They are biconcave and are present without a nucleus in human beings. It contain Haemoglobin which is an iron-rich protein due to which the color of blood is red. RBC’s are produced in the bone marrow which is mainly responsible for the transportation of oxygen to and from various tissues and organs present in the human body.

WBC (White Blood Cells)

WBC’s are also known as Leucocytes which are colourless blood cells due to the absence of haemoglobin. They are further divided into two categories such as granulocytes and agranulocytes. Their main responsibility is to provide immunity and maintain defence mechanisms in the human body.