Read the following passage and answer the questions that follow. Prevention is the frontline response to drug use. Effective interventions address the underlying conditions contributing to drug use, such as a lack of connection to family or community, instability, insecurity, trauma, mental health issues, etc. When addressed, these factors can effectively prevent the initiation of drug use and the progression to drug use disorders. Study the few key figures of drug use given below and answer the questions that follow.
(a) What do you infer from the figures in Table No. 1 about the people with drug use disorders, 2022 (in million)? State any two of your observations.
(b) How are Hepatitis C and HIV related to drug use disorders by people, as shown in Table No. 2? State the correlation between the two.
(c)
Around 292 million people used drugs in 2022, showing a 20% increase over the past decade.
Only 1 in 11 drug users receive treatment, with lower treatment rates for women (1 in 18) compared to men (1 in 7), indicating a significant treatment gap.
Drug injection increases the risk of transmission of blood-borne diseases such as HIV and Hepatitis C. Among 13.9 million people who inject drugs:
1.6 million are living with HIV.
1.4 million live with both HIV and Hepatitis C.
[(i)] The scientific name of (p) is Cannabis sativa. OR
[(ii)] The scientific name of (q) is Papaver somniferum.
Student to attempt either option (A) or (B):
(A) Give an account of the generalised structure of an antibody molecule produced by B-lymphocytes in response to the pathogen.
OR
(B) Other than public awareness and counselling, enlist four measures taken up by NACO, WHO and other NGOs to prevent the spread of HIV infection in the society.
Immunity in our body is of two types: (i) Innate immunity and (ii) acquired immunity. Innate immunity is a non-specific defence mechanism, whereas acquired immunity is pathogen-specific; it is called specific immunity too. Acquired immunity is characterised by memory. Antibodies are specific to antigens and there are different types of antibodies produced in our body: they are IgA, IgE, IgG and IgM. It shows primary response when it encounters the pathogen for the first time and secondary response during the subsequent encounters with the same Antigen/Pathogen.
(a) Name the two types of specialised cells which carry out the primary and secondary immune response.
(b) Why is the antibody-mediated immunity also called as humoral immune response?
Attempt either sub-part (c) or (d):
(c) The organ transplants are often rejected if taken from suitable compatible persons.
(i) Mention the characteristic of our immune system that is responsible for the graft rejection.
(ii) Name the type of immune response and the cell involved in it.
OR
(d) How is active immunity different from passive immunity?
Answer the following questions:
Student to attempt either option (A) or (B):
(A) Explain what is meant by the term amniocentesis. How is this technique misused in India?
OR
(B) Name any two VDs which might occur in a human female. State any two complications in a female if it is left untreated.