Question

Place the given stages of phagocytosis in the correct order of occurrence.

• A. [(A)] \textbf{Formation of Phagolysosome}
• B. [(B)] \textbf{Adherence to Microbe}
• C. [(C)] \textbf{Destruction of Microbe}
• D. [(D)] \textbf{Ingestion to form a phagosome}

Hint:

\textbf{Immunology: Phagocytosis.} Understanding the sequential steps of phagocytosis is fundamental to comprehending the innate immune response and how phagocytes eliminate pathogens and cellular debris.

Answer 1

The Correct Option is B

The correct order of the stages of phagocytosis is as follows: % Option (A) Chemotactic attraction of phagocyte (E): Phagocytes are attracted to the site of infection or inflammation by chemical signals (chemotaxis). % Option (B) Adherence to Microbe (B): The phagocyte's surface receptors bind to specific molecules on the surface of the microbe. % Option (C) Ingestion to form a phagosome (D): The phagocyte extends pseudopods that engulf the microbe, enclosing it within a membrane-bound vesicle called a phagosome. % Option (D) Formation of Phagolysosome (A): The phagosome fuses with lysosomes, which contain digestive enzymes, forming a phagolysosome. % Option (E) Destruction of Microbe (C): The microbe is killed and digested by the enzymes and other antimicrobial substances within the phagolysosome. Therefore, the correct order of occurrence is (E), (B), (D), (A), and (C).