Question:

Phosphodiester linkage that joins nucleotides together is present between which carbons of pentose sugar?

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Phosphodiester bonds are key to the structure of nucleic acids, connecting the sugar backbone of adjacent nucleotides in a DNA or RNA strand.
Updated On: Mar 12, 2025
  • 3', 3'
  • 5', 3'
  • 5', 2'
  • 3', 2'
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The Correct Option is B

Solution and Explanation

In nucleic acids, phosphodiester bonds link nucleotides together. These bonds form between the 3'-hydroxyl group of one nucleotide and the 5'-phosphate group of another nucleotide. Therefore, the linkage is between the 5' carbon of one sugar and the 3' carbon of the next sugar.
Thus, the correct answer is between the 5' and 3' carbons.
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