Question:

Patients suffering from cholera are given a saline drip because

Updated On: Jul 27, 2022
  • $Na^{+}$ ions help in stopping nerve impulses and hence, sensation of pain
  • $Na^{+}$ ions help in the retention of water in the body tissues
  • $NaCl$ is an important component of energy supply
  • $NaCl$ furnishes mot of the fuel required for cellular activity
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The Correct Option is B

Solution and Explanation

Severe diarrhoea, vomitting, watery stools are the chief symptoms of cholera. All these lead to dehydration. Actually, cholera toxin secreted by Vibrio cholerae causes, through a series of metabolic reactions, the continuous activation of adenylate cyclase of intestinal epithelial cells. The resultant high concentration of c-AMP triggers continuous secretion of $Cl ^{-}, HCO _{3}^{-}$and water into the lumen of the intestine. Administration of saline not only supports the sodium-potassium pump through which water in cell is restored, but glucose is also symported along with sodium.
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Concepts Used:

Common Diseases in Human Beings

Any adverse variation from an organism's normal structural or functional condition is usually associated with specific signs and symptoms and distinct from physical injury.

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A few diseases appear out of nowhere and persist only a few days. Acute diseases, such as the common cold, are examples of them. Acute diseases frequently become chronic if they are not treated.

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Acute diseases develop quickly and are accompanied by unique symptoms that necessitate immediate or short-term treatment and improve once treated. Acute illnesses, such as the common cold, can sometimes go away on their own.

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Chronic diseases are illnesses that develop over time and endure for a long time or even a lifetime. Chronic disease is defined as a disease that lasts more than three years. The symptoms are relatively modest at first.