Question

Oral vaccine such as Dukoral® and Shanchol™ is used for prevention of:

• A. $ \text{Pneumonia} $
• B. $ \text{Ebola virus} $
• C. $ \text{Cholera} $
• D. $ \text{Polio} $

Hint:

Remember that Dukoral® and Shanchol™ are the primary oral vaccines against cholera, critical for public health in endemic regions.

Answer 1

The Correct Option is C

Dukoral® and Shanchol™ are oral cholera vaccines designed to prevent cholera infection caused by Vibrio cholerae.
These vaccines stimulate mucosal immunity by inducing secretory IgA antibodies in the intestine, providing protection against cholera toxin. -

Dukoral® contains inactivated whole-cell Vibrio cholerae and recombinant cholera toxin B subunit.

Shanchol™ is a bivalent whole-cell oral vaccine without the toxin component.
These vaccines are effective in controlling cholera outbreaks, especially in endemic areas.

Other options:
Pneumonia vaccines target bacterial or viral causes like Streptococcus pneumoniae.
Ebola virus vaccine is different and not oral.
Polio vaccines (OPV) are oral but distinct from Dukoral/Shanchol.