In homeopathy, the term "one-sided disease" refers to conditions where the symptom picture is incomplete or lacks the characteristic totality required for a clear homeopathic prescription. According to Hahnemann:
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\item (C) Disease with few perceptible symptoms: One-sided diseases are often characterized by a paucity of clearly expressed symptoms, making it challenging to form a complete picture of the patient's suffering. The symptoms that are present may be vague or not strongly indicative.
\item (D) Less amenable to cure: Due to the lack of a clear and complete symptom totality, finding the simillimum (the most similar remedy) becomes difficult, which can make one-sided diseases less amenable to straightforward homeopathic cure.
\item (A) Disease which affect one side of the body: While some diseases may predominantly manifest on one side of the body, this is not the defining characteristic of a "one-sided disease" in homeopathic terminology. A well-characterized disease affecting one side could still present with a clear totality of symptoms.
\item (B) Disease which belong to class of Acute individual disease: One-sided diseases can be either acute or chronic and are defined by the lack of a complete symptom picture, not specifically by their acute nature.
\end{itemize}
Therefore, the most appropriate characteristics of one-sided diseases are that they present with few perceptible symptoms and are often less amenable to cure due to the difficulty in finding the simillimum.