Question

Name of the protein which holds two sister chromatids?

• A. Securine
• B. Separase
• C. Cohesin
• D. APC

Hint:

Cohesin holds sister chromatids together; separase cleaves it to allow separation.

Answer 1

The Correct Option is C

Cohesin is a protein complex that holds the two sister chromatids together after DNA replication, maintaining their cohesion until anaphase during cell division.
- Securin inhibits separase until anaphase.
- Separase cleaves cohesin to allow chromatid separation.
- APC (Anaphase Promoting Complex) regulates progression through mitosis.