Question:

Melonate inhibits the growth of pathogenic bacteria by inhibiting the activity of

Updated On: May 17, 2024
  • Amylase

  • Lipase

  • Dinitrogenase

  • Succinic dehydrogenase

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The Correct Option is D

Solution and Explanation

Melonate inhibits the growth of pathogenic bacteria by inhibiting the activity of Succinic dehydrogenase.

Succinic dehydrogenase, also known as succinate dehydrogenase or succinate-coenzyme Q reductase, is an enzyme involved in the electron transport chain and the tricarboxylic acid (TCA) cycle in bacteria. It catalyzes the conversion of succinate to fumarate, playing a crucial role in energy production.

Melonate is a competitive inhibitor of succinic dehydrogenase. It structurally resembles succinate and competes with it for binding to the active site of the enzyme. By binding to and inhibiting succinic dehydrogenase, melonate disrupts the normal functioning of the TCA cycle and electron transport chain, leading to a decrease in ATP production and inhibiting the growth of pathogenic bacteria.

Therefore, the correct option is (D): Succinic dehydrogenase

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Concepts Used:

Biomolecules

Biomolecules are the most essential organic molecules, which are involved in the maintenance and metabolic processes of living organisms. These non-living molecules are the actual foot-soldiers of the battle of sustenance of life.

There are four major classes of Biomolecules –  Carbohydrates, Proteins, Nucleic acids and Lipids.

  1. Carbohydrates are chemically defined as polyhydroxy aldehydes or ketones or compounds which produce them on hydrolysis.
  2. Proteins are another class of indispensable biomolecules, which make up around 50per cent of the cellular dry weight. Proteins are polymers of amino acids arranged in the form of polypeptide chains. The structure of proteins is classified as primary, secondary, tertiary and quaternary in some cases.
  3. Nucleic acids refer to the genetic material found in the cell that carries all the hereditary information from parents to progeny. There are two types of nucleic acids namely, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The main function of nucleic acid is the transfer of genetic information and synthesis of proteins by processes known as translation and transcription.
  4. Lipids are organic substances that are insoluble in water, soluble in organic solvents, are related to fatty acids and are utilized by the living cell.