Question

Match the following antibodies with their correct description:

Antibody	Description
P. IgE	(i) Cross the placenta
Q. IgG	(ii) Dominant antibody produced in immune responses
R. IgM	(iii) It is found in the mother's milk
S. IgA	(iv) Responsible for autoimmune responses including allergies

• A. P(iv), Q(ii), R(iii), S(i)
• B. P(iii), Q(ii), R(iv), S(i)
• C. P(i), Q(ii), R(iii), S(iv)
• D. P(ii), Q(i), R(iii), S(iv)

Hint:

- IgE is involved in allergic reactions, IgG crosses the placenta, IgM is the first response antibody, and IgA is present in mucosal areas like breast milk.
- These antibodies are crucial in different stages and aspects of immune responses.

Answer 1

The Correct Option is D

The following are the descriptions for each antibody: 
- P. IgE: (iv) Responsible for autoimmune responses including allergies. IgE is mainly involved in allergic reactions and immune responses to parasites. 
- Q. IgG: (i) Cross the placenta. IgG is the only antibody class that can cross the placenta, providing passive immunity to the fetus. 
- R. IgM: (ii) Dominant antibody produced in immune responses. IgM is the first antibody produced in response to an infection and is crucial in the early immune response. 
- S. IgA: (iii) It is found in the mother's milk. IgA is the primary antibody found in mucosal areas, including mother's milk, where it provides passive immunity to the newborn.

 Thus, the correct matching is P(iv), Q(i), R(ii), S(iii).