Step 1: Recall the role of each enzyme.
- Chymosin: Used in coagulating milk proteins, especially in cheese manufacturing.
- Thermolysin: A thermostable protease, used for peptide bond formation, specifically in aspartame synthesis.
- β-Galactosidase: Breaks down lactose into glucose and galactose, used in lactose hydrolysis.
- Lipase: Catalyzes esterification and hydrolysis of fats, used in acyl glycerol restructuring.
Step 2: Match with Column II.
- P (Chymosin) → 4 (Cheese manufacturing)
- Q (Thermolysin) → 3 (Aspartame synthesis)
- R (β-Galactosidase) → 2 (Lactose hydrolysis)
- S (Lipase) → 1 (Acyl glycerol restructuring)
Final Answer:
\[
\boxed{\text{(A) P-4, Q-3, R-2, S-1}}
\]