Question

Insulin action on a target cell causes an increase in

• A. Acetyl CoA carboxylase
• B. Glucokinase
• C. Glucose-6-phosphate dehydrogenase
• D. GLUT4 transporter

Hint:

Insulin promotes glucose uptake by increasing the number of GLUT4 transporters on the cell membrane.

Answer 1

The Correct Option is A, B, C, D

Step 1: Insulin's Role in Cells.
Insulin stimulates the uptake of glucose into cells by increasing the number of GLUT4 transporters on the cell surface. This enhances glucose entry into muscle and adipose cells.
Step 2: Analyzing the Options.
- (A) Incorrect. Insulin regulates acetyl-CoA carboxylase, but this is related to fatty acid synthesis.
- (B) Incorrect. Glucokinase is involved in glucose phosphorylation, but insulin’s primary effect is on GLUT4 transporters.
- (C) Incorrect. Glucose-6-phosphate dehydrogenase is involved in the pentose phosphate pathway, not in insulin signaling.
- (D) Correct. Insulin promotes the translocation of GLUT4 transporters to the cell membrane, increasing glucose uptake.
Step 3: Conclusion.
Thus, the correct answer is (D).