Question:

In a DNA molecule, which of the following base-pairings is correct?

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Remember the base pairing rules: In DNA, A pairs with T and G pairs with C. This is known as complementary base pairing and is fundamental to the structure of the DNA molecule.
Updated On: Apr 15, 2025
  • Adenine pairs with Cytosine.
  • Thymine pairs with Guanine.
  • Adenine pairs with Thymine.
  • Cytosine pairs with Uracil.
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The Correct Option is C

Solution and Explanation

In the DNA double helix, the base-pairing rules are governed by hydrogen bonds between nitrogenous bases. The correct base pairings in DNA are:

  • Adenine (A) pairs with Thymine (T) through two hydrogen bonds.
  • Guanine (G) pairs with Cytosine (C) through three hydrogen bonds.

Thus, the correct base pairing is: Adenine pairs with Thymine, and Guanine pairs with Cytosine.

The incorrect options are:

  • Option (1): Adenine does not pair with Cytosine. Instead, Adenine pairs with Thymine.
  • Option (2): Thymine does not pair with Guanine. Instead, Thymine pairs with Adenine.
  • Option (4): Cytosine does not pair with Uracil. Cytosine pairs with Guanine in DNA, whereas Uracil is found in RNA, where it pairs with Adenine.

Thus, the correct answer is Option (3).

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