Step 1: Understanding the role of factors.
During protein synthesis, the factors R1, R2, and S play an important role in the elongation and termination of protein chains. These factors are involved in processes like the release of the polypeptide chain after synthesis is completed.
Step 2: Analyzing the options.
(A) formation of amino acid t-RNA complex: This is related to the initial stages of protein synthesis but is not directly related to the role of factors R1, R2, and S.
(B) release of polypeptide chain: Correct. The factors R1, R2, and S are involved in the termination phase, where the polypeptide chain is released.
(C) initiation of transcription: This is incorrect as the factors R1, R2, and S are involved in translation, not transcription.
(D) linking codon with anticodon: This is part of the translation process but does not directly involve the mentioned factors.
Step 3: Conclusion.
The correct answer is (B) release of polypeptide chain.