Question

(ii) Explain the role of hormones in spermatogenesis.

Hint:

Hormonal regulation is crucial for the proper initiation and maintenance of spermatogenesis.

Answer 1

Hormonal regulation is crucial for spermatogenesis. The process involves the following hormones: \begin{itemize} \item GnRH (Gonadotropin-Releasing Hormone): Secreted by the hypothalamus, it stimulates the anterior pituitary to release FSH and LH. \item FSH (Follicle-Stimulating Hormone): Acts on Sertoli cells to promote spermatogenesis and produce androgen-binding protein (ABP), which maintains high testosterone levels in the seminiferous tubules. \item LH (Luteinizing Hormone): Stimulates Leydig cells in the testes to produce testosterone. \item Testosterone: Essential for the maturation of sperm cells and feedback regulation of GnRH, FSH, and LH levels. \item Inhibin: Secreted by Sertoli cells, it specifically regulates FSH secretion to maintain hormonal balance. \item Prolactin: Enhances the sensitivity of Leydig cells to LH, indirectly supporting testosterone production. \end{itemize} Disruptions in these hormonal levels can impair sperm production and lead to infertility. Hormonal therapies can help restore balance and normal spermatogenesis. % Quick tip