Question:

If the total amount of adenine and thymine in a double-stranded DNA is $45\%$, the amount of guanine in this DNA will be

Updated On: May 20, 2022
  • $22.5\%$
  • $27.5\%$
  • $45\%$
  • $55\%$
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The Correct Option is B

Solution and Explanation

According to Chargaffs rule
$A + G = T + C$
$ A+G=T+C$
In the given ds- DNA, the total amount of adenine and thymine is $45 \%$,
thus, the remaining $55 \%$ will be of cytosine and guanine.
Out of which, $27.5 \%$ ( $55 / 2$ ) will be of guanine.
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Concepts Used:

Structure of DNA and RNA

DNA Structure:

Human DNA is unique and is made up of 3 billion base pairs. However, 99% of them are the same in all humans. The sequence of these bases determines what information needs to be coded that is necessary for the organism's growth and development. During the process of transcription (when DNA is replicated), a product is formed known as RNA (Ribonucleic Acid). This RNA is responsible for translating genetic information from DNA to protein followed by reading through ribosomes. 

Read More: Structure of DNA

RNA Structure:

The ribonucleic acid has all the components same to that of the DNA with only 2 main differences within it. RNA has the same nitrogen bases called the adenine, Guanine, Cytosine as that of the DNA except for the Thymine which is replaced by the uracil. Adenine and uracil are considered as the major building blocks of RNA and both of them form base-pair with the help of 2 hydrogen bonds.

RNA resembles a hairpin structure and like the nucleotides in DNA, nucleotides are formed in this ribonucleic material(RNA). Nucleosides are nothing but the phosphate groups which sometimes also helps in the production of nucleotides in the DNA.

Read More: Structure of RNA