Question:

If a colour blind female marries a man whose mother was also colour blind, what are the chances of her progeny having colour blindness?

Updated On: May 2, 2025
  • 25%
  • 50%
  • 75%
  • 100%
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The Correct Option is D

Solution and Explanation

To determine the probability of progeny having color blindness, we must understand the genetics behind the condition. Color blindness is a sex-linked recessive trait carried on the X chromosome. Let's denote the normal vision allele as XN and the color blindness allele as Xc.
For a female to be color blind, she must have two copies of the Xc allele (XcXc). A male is color blind if he has an Xc allele, as his genotype is XcY.
The female in this scenario is color blind (XcXc), and the male's mother was color blind, meaning he must have inherited the Xc from her. Therefore, his genotype is XcY.
We will analyze the possible genotypes of their progeny:
  • A son will inherit an X chromosome from his mother and a Y chromosome from his father.
  • A daughter will inherit an X chromosome each from both parents.
Parental Genotypes: Female (XcXc) and Male (XcY)
ParentsXc (Mother)Xc (Mother)
Xc (Father)XcXcXcXc
Y (Father)XcYXcY
From this cross, all daughters (XcXc) will be color blind, and all sons (XcY) will be color blind because they inherit the Xc allele. Therefore, 100% of their progeny will be color blind.
The correct answer is 100%.
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