Question:

H1 receptor protein in humans is made up of:

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- The H1 receptor is a G-protein coupled receptor (GPCR) composed of 487 amino acids. - Understanding the structure of receptors like H1 is crucial in pharmacology, particularly in the design of antihistamines.
Updated On: Feb 4, 2025
  • 487 Aminoacids
  • 390 Aminoacids
  • 445 Aminoacids
  • 359 Aminoacids
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The Correct Option is A

Solution and Explanation

The H1 receptor is a type of histamine receptor found in humans and plays a significant role in various physiological functions, including immune responses and neurotransmission. The H1 receptor protein is a G-protein coupled receptor (GPCR), and it is composed of 487 amino acids. This receptor is involved in mediating the effects of histamine, such as vasodilation and contraction of smooth muscles, which are integral in allergic reactions and inflammation. 

Why Other Options Are Incorrect: -
- (B) 390 Aminoacids: This is not the correct number of amino acids for the H1 receptor protein. 
- (C) 445 Aminoacids: Although a close number, this is not the correct length of the H1 receptor protein. 
- (D) 359 Aminoacids: This is also incorrect for the H1 receptor protein's length. 

Thus, the correct answer is 487 amino acids, which is the precise length of the human H1 receptor protein.

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