Question

Given below are two statements: One is labelled as Assertion (A) and the other is labelled as Reason (R).
Assertion (A) : Pancreatitis is inflammation of the parenchyma of the pancreas.
Reason (R) : The underlying mechanism of injury in pancreatitis is thought to be premature activation of pancreatic enzymes within the pancreas, leading to process of autodigestion.
In the light of the above statements, choose the correct answer from the options given below:

• A. Both (A) and (R) are true and (R) is the correct explanation of (A)
• B. Both (A) and (R) are true but (R) is NOT the correct explanation of (A)
• C. (A) is true but (R) is false
• D. (A) is false but (R) is true

Hint:

Pancreatitis = inflammation by autodigestion due to early enzyme activation.

Answer 1

The Correct Option is A

Assertion (A) is true because pancreatitis is, by definition, the inflammation of the pancreatic tissue (parenchyma).
Reason (R) is also true — the main mechanism for injury in acute pancreatitis is the premature activation of digestive enzymes like trypsin within the pancreas.
These activated enzymes cause the pancreas to digest itself, which is known as autodigestion.
This mechanism directly explains the inflammation described in (A).
Therefore, both the Assertion and the Reason are true, and (R) correctly explains (A).
So, option (1) is the correct answer.