The vowels in the word OMEGA are O, E, and A, and they must occupy the odd places.
There are 3 odd positions, so the vowels can be arranged in 3! = 6 ways.
The remaining consonants (M, G) can be arranged in the 2 even places in 2! = 2 ways.
Thus, the total number of permutations is \(3! × 2! = 12.\)