The correct option to complete the sentence is “which.”
So, the complete sentence is: “There are many inventions of science which have benefitted human beings in many ways.”
The word “which” is used to introduce a relative clause that provides more information about the inventions.
Using “which” correctly links the clause to the noun “inventions,” specifying the particular inventions that have had benefits.
The other options, “those” and “such,” do not fit grammatically in this context as relative pronouns introducing clauses.