Step 1: Explanation. - Each individual has two alleles for a trait (one from each parent). - During gamete formation (meiosis), these alleles segregate randomly. - Hence, each gamete carries only one allele for the given trait. - Fertilization restores the pair of alleles in the offspring.
Step 2: Example (Monohybrid Cross). Consider Mendel's experiment with pea plants: - Cross between a homozygous tall plant (TT) and a homozygous dwarf plant (tt). - F$_{1}$ generation: All plants are heterozygous (Tt), showing tallness. - F$_{2}$ generation (selfing of Tt): The ratio obtained is \[ \text{Genotypic ratio: } 1 \; TT : 2 \; Tt : 1 \; tt \] \[ \text{Phenotypic ratio: } 3 \; Tall : 1 \; Dwarf \] This shows that alleles separate during gamete formation and recombine at fertilization.
Final Answer: \[ \boxed{\text{Mendel's Law of Segregation states that alleles separate during gamete formation, and each gamete receives only one allele.}} \]
1. Perform a cross between two sickle cell carriers. What ratio is obtained between carrier, disease free and diseased individuals in F1 progeny? Name the nitrogenous base substituted, in the haemoglobin molecule in this disease.
2. Explain the difference in inheritance pattern of flower colour in garden pea plant and snap-dragon plant with the help of monohybrid crosses.
OR,
Explain with the help of well-labelled diagrams how lac operon operates in E. coli :
1. In presence of an inducer.
2. In absence of an inducer.
Study the pedigree chart given below, showing the inheritance pattern of blood group in a family:

Answer the following questions:
(a) Give the possible genotypes of individual 1 and 2.
(b) Which antigen or antigens will be present on the plasma membranes of the R.B.Cs of individuals ‘5’ and ‘8’?
The sequence of nitrogenous bases in a segment of a coding strand of DNA is
5' – AATGCTAGGCAC – 3'. Choose the option that shows the correct sequence of nitrogenous bases in the mRNA transcribed by the DNA.