Question:
“DNA replication is continuous and discontinuous on the two strands within the replication fork.” Explain with the help of a schematic representation.
“DNA replication is continuous and discontinuous on the two strands within the replication fork.” Explain with the help of a schematic representation.
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The antiparallel nature of DNA strands necessitates continuous and discontinuous replication in the fork structure.
Updated On: Jan 18, 2025
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Solution and Explanation
Leading strand: Synthesised continuously in the 5\(\prime\) to 3\(\prime\) direction.
Lagging strand: Synthesised discontinuously in short fragments (Okazaki fragments) and later joined by DNA ligase.
\[
\text{Diagrammatic representation should include the fork, helicase, and synthesis direction.}
\]
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