Step 1: Innate Immunity is the first line of defense. It includes physical barriers (skin), physiological barriers (stomach acid), cellular barriers (WBCs), and cytokine barriers (interferons).
Step 2: Acquired Immunity is the second line of defense developed during an individual's lifetime. It involves specialized B-lymphocytes and T-lymphocytes.
Step 3: A key difference is "memory": Acquired immunity remembers a pathogen so that a second encounter triggers a highly intensified (secondary/anamnestic) response.