Question

Diazepam is synthesized from \ldots

• A. Diphenyl methane
• B. 2-Amino-5-chloro benzophenone
• C. 3-Chloro acetophenone
• D. Phenothiazine

Hint:

Diazepam’s synthesis involves forming a seven-membered diazepine ring, which is key to its pharmacological activity.

Answer 1

The Correct Option is B

Diazepam, a benzodiazepine used for anxiety and sedation, is synthesized starting from 2-amino-5-chloro benzophenone. This compound undergoes a series of reactions, including condensation with chloroacetyl chloride and cyclization, to form the benzodiazepine ring structure of Diazepam. Diphenyl methane, 3-chloro acetophenone, and phenothiazine are not precursors in this synthesis pathway.
Thus, the correct answer is 2-Amino-5-chloro benzophenone.